This can be very helpful if you want to automate mouse clicks for editing multiple files, data entry, or even games. View more View less What is an Auto Clicker for MacĪn auto clicker is actually an app that simulates mouse clicks when needed. How do I use a keyboard shortcut to activate an auto clicker?.What is the difference between mouse and auto clickers?.Automation on Mac Made Easy with Auto Clickers.Do I Even Need an Auto Clicker on My Mac?.